Molecular Virology

1 Introduction. - 1. 1 Historical development of molecular virology. - 1. 2 What is a virus?. - 1. 3 Titration of viruses. - 1. 4 Virus-host interactions. - 2 The virion. - 2. 1 Principles of virion construction. - 2. 2 Special features of virion anatomy. - 2. 3 Viral nucleic acids. - 2. 4 The virion: function. - 3 The virus-infected cell. - 3. 1 Transcription and translation in the virus-infected cell. - 3. 2 Post-translational modification of proteins. - 3. 3 Genome replication. - 3. 4 Virus assembly. - 3. 5 Virus release. - 3. 6 Temperate phage and lysogeny. - 4 Virus genetics. - 4. 1 Mutations. - 4. 2 Functional or complementation analysis. - 4. 3 Fundamental studies in recombination. - 4. 4 Chromosome mapping. - 4. 5 Genetic recombination. - 5 Tumour virology. - 5. 1 What is a tumour?. - 5. 2 Causation of tumours. - 5. 3 Papovaviruses. - 5. 4 RNA tumour viruses. - 5. 5 Comparison of transformation by DNA and RNA tumour viruses; oncogene theory. - Suggestions for further reading. Language: English